After 11 straight wins, Sporting’s Primeira Liga title defence suffered its first setback as the sensational Santa Clara pulled off a shock 1-0 victory at Alvalade.
Vinícius Lopes put the Azorean team ahead in the 33rd minute with a ferocious shot that left Vladan Kovacevic rooted to his spot.
Sporting could find no way back and looked physically and mentally drained well before the end of the match, in contrast to a superbly organised Santa Clara who remained composed under pressure and were always a threat on the break.
With two defeats in his first three matches, it is far from an ideal start to life as new Sporting coach for João Pereira.
Hoffenheim left northern Portugal for the second time in recent weeks with their tails between their legs after Braga got their Europa League campaign back on track with a 3-0 victory over the Germans at the Quarry tonight.
Under-pressure Porto coach Vítor Bruno saw his side twice take the lead against Anderlecht in Belgium this evening, but the Dragons could not hold on for victory, leaving them in a precarious position in the lower reaches of the Europa League table.
Astana 1-1 Vitória
Benfica got back to winning ways in the UEFA Champions League after a thrilling 3-2 win in Monaco.